TOPCAT CLINICAL TRIAL TRIAL

In the United States, a clinical trial must have an IRB if it is studying a drug, biological product, or medical device that the Food and Drug Administration (FDA) regulates, or it is funded or carried out by the federal government. Make sure that the risks are reasonable when compared to the potential benefits.Search for clinical trials in seconds by medical condition, featured clinical institution, and more. Protect the rights and welfare of the participants Getting connected to open clinical trials near you has never been easier. The Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist trial (TOPCAT) observed a minor reduction (HR0.89) for adverse clinical outcome in spironolactone arm without reaching statistical significance.Because of regional variations in the enrollment process and difficulties regarding drug adherence the trial revealed neutral findings but the substance spironolactone was still able to show its potential. It is an independent committee of physicians, statisticians, and members of the community. In 2013 the TOPCAT investigators tried to proof similar efficacy in patients with heart failure and preserved ejection fraction ( 45). Others want just men or just women.ДЄn Institutional Review Board (IRB) reviews, monitors, and approves many clinical trials. Some studies need volunteers with a certain disease. Has its own rules about who can take part. Will be done in the study, how it will be conducted, and why each part of the study is necessary. Clinical trials may also compare a new treatment to a treatment that is already available.Д®very clinical trial has a protocol, or action plan, for conducting the trial. Each studyДЄnswers scientific questions and tries to find better ways to prevent, screen for, diagnose, or treat aДisease. Clinical trials are research studies that test how well new medical approaches work in people.

Topcat clinical trial